A Story with 3 Genres

Image by Jeff Bauche._.·´¯) via Flickr

An idea hit me. One that I love. One that I really want to write, but I have one little problem...

I am not sure what genre to set it in!! The basic idea is to explore spirituality, power, and the power of relationships to save people.

I know that is a little vague, but it is a complex story with a generic outline that spans four novels at the moment.

My biggest problem is that I can see the story existing in three different settings

1. My existing Barrens End setting, where Liquid Sky, Fate's Harrow, and Shine like Thunder take place.

2. A new modern supernatural horror setting that would be somewhere between the Vampire Chronicles, Harry Potter, and the Cthulu Mythos.

3. A unique hybrid fantasy setting, a kind of sword and sorcery/dark fantasy/supernatural horror/steampunk thing.

I can honestly see the story in each of these settings, and how each will affect the plot. I am partly looking for comments, and part thinking out loud. I am really unsure which way to go.

What would you all like to see?  I am really open to suggestions